Omega 3-6 

-Both omega 3 and omega 6 fatty acids are essential components of the cell membrane, playing a role in balancing the inflammatory response and blood pressure due to their ability to reduce cytokine release. 
 
Omega-3 essential fatty acids, such as docosahexaenoic acid and escosapentaenoic acid, reduce the risk of heart attack, death, and arrhythmias by directly reducing blood triglycerides, which are fatty substances that have been shown to narrow arteries and contribute to blood clots, slowing the formation of atherosclerotic plaques, and slightly lowering blood pressure. 
 
-It is effective in muscle growth by causing a significant increase in anabolic response with the positive correlation between omega-3 supplement and protein synthesis. It also significantly increases growth hormone production. 
 
-It helps protect the eyes from age-related vision loss, dry eye syndrome and reduces the risk of high eye pressure and glaucoma. 
 
-It has many brain-strengthening benefits, improving age-related cognitive decline, depression and mood disorders. 
 
- Omega3 fatty acids down-regulate pro-inflammatory cytokines and protect against bone loss by reducing osteoclast activation and bone reabsorption. 

Vitamin E 

-Vitamin E may have protective effects against cataracts and glaucoma. 
 
-In addition to its antioxidative activities, vitamin E has anti-inflammatory, antiplatelet, anticancer, osteo- and neuroprotective effects. 

Vitamin A 

-Vitamin A is necessary for normal bone metabolism. 

Vitamin D3 

-Vitamin D is a secoteriod hormone required for calcium absorption and bone mineralization, which is positively associated with bone mineral density; It increases the absorption of calcium, magnesium and phosphorus and activates calcium and phosphorus in the bone. 
 
Osteoporosis is often considered an inflammatory condition, and proinflammatory cytokines have been associated with increased bone metabolism. The immunoregulatory mechanisms of vitamin D modulate the effect of cytokines on bone health and subsequent fracture risk.